Ossama Maher, MD - Pediatric Neuro-Oncologist

 

Pediatric Neuro Oncologist

Dr. Maher is the associate clinical director of the Neuro-Oncology Program, which provides state-of-the-art treatment for all newly diagnosed and recurrent brain tumors in pediatrics. Dr. Maher received his medical degree from Faculty of Medicine, Cairo University.  He completed his residency at the Brooklyn Hospital Center, New York and his fellowship in Hematology-Oncology at MD Anderson Cancer Center in Houston, Texas. Dr. Maher also completed a combined pediatric Neuro oncology/ stem cell transplant fellowship at Dana- Faber Cancer Institute, Harvard medical school.

Dr. Maher is a member of the American Society Hematology, American Society of Clinical Oncology, American Society of Pediatric Hematology Oncology and the Society of Neuro-Oncology. Dr. Maher is board certified in General Pediatrics and Pediatric Hematology and Oncology. Dr. Maher participates in conducting research studies and stem cell transplantation for children with brain tumors.

Dr. Maher sees patients at Nicklaus Children’s Hospital. He is fluent in English, Arabic and French.

Abstract

  1. Ossama M. Maher, Hani Hussein, Sean A Marco, Aziza Sedrak, Yasser E Elborai, Heba Moussa & Alaa El-Haddad. Role of High Dose Methotrexate with Cranial Irradiation for Pediatric T-Cell Lymphoid Malignancies.“http://bloodjournal.hematologylibrary.org/site/misc/ASH_Meeting_Abstracts_Info.xhtml” December 2012 and is part of the permanent ASH and Blood abstracts archive.
  2. Yasser Elborai, Mohammad Almutereen, Ossama Maher, Alaa El-Haddad, Leslie Lehmann. Changes in GFR during carboplatin administration in children undergoing autologous stem cell transplant (SCT) for malignant brain tumor. Pediatr Blood Cancer DOI 10.1002/pbc (Pub 204) page 16-17. Oct 2012 SIOP publication abstracts. 2012 Wiley Periodicals, (wileyonlinelibrary.com).
  3. Ossama M.  Maher, Sean Marco, Swayam Sadanandan, Fernando Fireman, Aziza Sedrak. Retroperitoneal Ganglioneuroma and Reversible Posterior Leukoencephalopathy in a Child with Acute Lymphoblastic Leukemia. The Brooklyn Hospital Center, Brooklyn, New York. American Society of Pediatric Hematology (ASPHO) meeting- April 24-27, 2013- Miami - Florida.
  4. Ossama M. Maher, Hani Hussein, Sean A Marco, Aziza Sedrak, Yasser Elborai, Heba Moussa, Alaa El-Haddad. Rotating Chemotherapy Agents and Cranial Irradiation with Pediatric Lymphoblastic Malignancies at the National Cancer Institute, Cairo University. National Cancer Institute, Cairo University, Egypt. American Society of Pediatric Hematology (ASPHO) meeting- April 24-27, 2013- Miami, FL.
  5. Yasser Elborai, Andrew Blanchette, Ossama M. Maher, Leslie Lehmann, and Michelle Lee. Renal and Bone Marrow Toxicity in pediatric HSCT patients on acyclovir prophylaxis. Ped Onc, National Cancer Institute, Cairo University, Cairo, Egypt; Ped HSCT, Dana Farber Cancer Institute, Harvard University, Boston, United States and Pediatrics, Brooklyn Hospital Center, NY, United States. American Society of Pediatric Hematology (ASPHO) meeting -April 24-27, 2013- Miami, FL.
  6. Ossama M. Maher, Laurence J.N. Cooper, Laura Worth, Demetrios Petropoulos, Dean A. Lee , Richard E. Champlin, Nidale Tarek, Priti Tewari.  Successful Treatment for Secondary AML and MDS following myeloablative Hematopoetic Stem Cell Transplantation for Children, Adolescents and Young Adults. MD Anderson Cancer Center, Houston, Texas. European Bone Marrow Transplant (EBMT) Meeting- March 20- April 2, 2014- Milan, Italy.
  7. Ossama M. Maher, Hany Hussein, Aziza Sedrak, Yasser Elborai, Heba Moussa, Alaa El-Haddad. Assessment of early steroid responsiveness in Children with T- Cell Acute Lymphoblastic Leukemia- National Cancer Institute- Cairo University experience. National Cancer Institute, Cairo University. American Society of Pediatric Hematology (ASPHO) meeting- May 14- 17, 2014- Chicago, Illinois
  8. Ossama M. Maher, Cynthia E. Herzog. Metastatic Angiomatoid variant of Fibrous Histiocytoma with CREB1 gene rearrangement. MD Anderson Cancer Center, Houston, Texas. American Society of Pediatric Hematology (ASPHO) meeting- May 14- 17, 2014- Chicago, Illinois.
  9. Hatel Rana Moonat, Ossama M. Maher, Alaa Abdullah Almohammedsalim, Soumen Khatua, Wafik Zaky, Infection Mimicking Malignancy MD Anderson Cancer Center, Houston, Texas. American Society of Pediatric Hematology (ASPHO) meeting -May 14- 17, 2014- Chicago, Illinois.
  10. Ossama M. Maher, Soumen Khatua, Nidale Tarek, Wafik Zaky. Metachronous Medullobastoma in a child with metastatic neuroblastoma. MD Anderson Cancer Center, Houston, Texas 16th International Symposium on Pediatric Neuro-Oncology (ISPNO) meeting -June 28- July 2, 2014- Singapore.
  11. Ossama M. Maher, Soumen Khatua, Wafik Zaky. Challenges and opportunities of molecularly targeted therapy in recurrent or refractory pediatric brain tumors. MD Anderson Cancer Center, Houston, Texas 16th International Symposium on Pediatric Neuro-Oncology (ISPNO) meeting- June 28- July 2, 2014- Singapore.
  12. Ossama M. Maher, David Sandberg, Geoffrey Kannan, Susan McGovern, Leena Ketonen, Soumen Khatua, Wafik Zaky. Primary Leptomeningeal Primitive Neuroectodermal Tumor. MD Anderson Cancer Center, Houston, Texas 9 th Annual scientific meeting. The Society for Neuro-Oncology (SNO) November 13-16, 2014. Miami- FL.
  13. Ossama M. Maher, Soumen Khatua, Wafik Zaky. Primary intracranial soft tissue sarcoma in children and young adults: Retrospective analysis. MD Anderson Cancer Center experience. MD Anderson Cancer Center, Houston, Texas 9 th Annual scientific meeting. The Society for Neuro-Oncology (SNO) November 13-16, 2014. Miami- FL.
  14. Ossama M. Maher, Mary McAleer, David Sandberg, Leena Ketonen, Soumen Khatua, Wafik Zaky. Targeted therapy in Glioblastoma multiforme presenting as Gliomatosis Cerebri. MD Anderson Cancer Center, Houston, Texas 9 th Annual scientific meeting. The Society for Neuro-Oncology (SNO) - November 13-16, 2014. Miami- FL.
  15. Ossama M. Maher, Jorge Galvez Silva, Chloe Tillman, Laurence Cooper, Laura L. Worth,  Demetrios Petropoulos,  Dean A. Lee,  Richard E. Champlin, Nidale Tarek, Priti Tewari.  Incidence and outcome of early hospital readmission following hematopoietic stem cell transplantation in pediatric and young adults. MD Anderson Cancer Center, Houston, Texas. Annual meeting of the American Society for Blood and Marrow Transplantation (ASBMT) and the Center for International Blood & Marrow Transplant Research (CIBMTR) - February 11 - 15, 2015. San Diego, California.
  16. Dat Q Tran, Ossama M. Maher, Charlotte Rivas, Shannon Elizabeth Moree. Reduced and skewed TCR Vβ repertoire in CD8 compared to Foxp3+ regulatory T cells in acute gastrointestinal graft versus host disease. University of Texas Medical School of Houston; MD Anderson Cancer Center, Houston, Texas. American Academy of immunologies (AAI) - May 8-12, 2015. New Orleans, LA.
  17. Jorge G. Silva, Ossama M. Maher, Chloe Tillman, Laurence JN. Cooper, Nidale Tarek, Laura L. Worth, Demetrios Petropoulos, Dean A. Lee, Richard E. Champlin, EJ. Shpall3, Priti Tewari. Evaluation and Analysis of Causes of Early Readmission Following Umbilical Cord Blood Transplantation in Children, Adolescents and Young Adults. MD Anderson Cancer Center, Houston, Texas - American Society of Pediatric Hematology/ Pediatric Blood and Marrow Consortium ASPHO/PBMTC meeting- Phoenix- Arizona-May 2015.
  18. Ossama M. Maher, Shannon Moree, BA, Charlotte H Rivas, BS, Magdalena Esparza and Dat Tran, MD. Reduced and Skewed TCR Vβ Repertoire in CD8 Compared to CD4 and Foxp3+ Regulatory T Cells in Acute Gastrointestinal Graft Versus Host Disease. MD Anderson Cancer Center, Houston, Texas; University of Texas Medical School of Houston- Federal of clinical Immunology Societies (FOCIS)-June 24-27, 2015. San Diego, California.
  19. Jorge Galvez Silva, Ossama M. Maher, Minjeong Park, MS, Diane Liu, MS, Fiorela Hernandez MD, Priti Tewari, MD, Yago Nieto, MD PhD. Analysis of the Prognostic effect of Peripheral Blood Lymphocyte and Monocyte Count after Autologous Hematopoietic Stem Cell Transplant in Refractory/Relapsed Hodgkin's Lymphoma in a Pediatric, Adolescent, and Young Adult Population. Annual meeting of the American Society for Blood and Marrow Transplantation (ASBMT) - February 18 - 22, 2016. Honolulu, Hawaii.
  20. Ossama M. Maher, Rima M. Saliba, Amin Alousi, Richard E.Champlin, Elizabeth J. Shpall, Priti Tewari, Sharon R. Hymes, Joyce Neumann, Overman Bethany, Julianne Chen, Gabriela Rondon, Hyo W Song,Colby J Hofferek, and Dat Q Tran. High TCR Vbeta skewing in CD4+ and low in CD8+ is associated with development of chronic graft-versus-host disease. Annual meeting of the American Society of Hematology (ASH) - December 3-6, 2016. San Diego, California.
  21. Divyaswathi Citla Sridhar, Ossama M. Maher, Nidra I. Rodriguez. Pediatric venous thrombosis associated with staphylococcal infections: Single institutional experience. American Society of Pediatric Hematology (ASPHO) meeting - April 26 -29, 2017- Montreal, Quebec, Canada.
  22. Higher frequency of switched memory B cells predicts the incidence of chronic graft –versus-host disease after allogeneic stem cell transplantation. Rima M. Saliba, Hyo W. Song, Ossama M. Maher, Bethany J. Overman, Colby J. Hofferek, Anha V. Pham,Julianne Chen, EJ Shpall, Issa F. Khouri, Richard E. Champlin, Betul Oran, Sairah Ahmed, Amin M. Alousi, Dat Q.Tran. Oral presentation European Hematology Association (EHA) meeting- June 22-25, 2017- Madrid-Spain.

Oral Presentations

  • Ossama Maher, Sherif Abou El Naga, Soha Emam. (March, 2004). 1st line antimicrobial therapy for febrile neutropenic cancer patients. Oral Presentation presented at: Master's project of pediatric discussion; Cairo, Egypt.
  • Ossama Maher, Lobna Shalaby (November, 2008). Treatment of Newly diagnosed cases of Anaplastic Large Cell Lymphoma at the National Cancer Institute. Poster presented at: Pediatric Grand Round Meeting; Cairo, Egypt.
  • Ossama Maher, Alaa El Haddad, Hani Hussein, (February, 2009). Treatment of Newly diagnosed cases of advanced cases of lymphoblastic lymphoma and T-Cell acute lymphoblastic leukemia at the National Cancer Institute. Oral Presentation presented at: PHD thesis discussion; Cairo, Egypt.
  • Ossama Maher, Role of single dose Azithromycin in treatment of children with otitis media. Journal Club presentation. The Brooklyn Hospital Center. Brooklyn New York, April 2012.
  • Ossama Maher, Comparison of Piperacillin – Tazobcatam Vs Cefepime in febrile neutopenic cancer patient. Critically appraised topic (CAT), December 2012 The Brooklyn Hospital Center. Brooklyn New York, December 2013.
  • Ossama Maher, How to write a case report. National Cancer Institute, April 2013, Cairo University, Cairo, Egypt.
  • Ossama Maher, Review of important topics in Pediatric Oncology. The Brooklyn Hospital Center, Brooklyn, New York. May 2013.
  • Ossama Maher, Nut midline carcinoma. Tumor Board Presentation. MD Anderson Cancer Center, Houston, Texas. November 2013.
  • Ossama M. Maher, Jorge Galvez, Laurence Cooper, Laura L. Worth, Demetrios Petropoulos, Dean A. Lee, Richard E. Champlin, Nidale Tarek, Priti Tewari. Successful treatment for Secondary AML and MDS following myeloablative Hematopoetic Stem Cell Transplantation for Children, Adolescents and Young Adults. Oral presentation- ASPHO/PBMTC meeting- Phoenix- Arizona. May 2015.

Awards

  • Dean’s Honor List: Kasr El-Aini School of Medicine: Cairo University, Cairo, Egypt. - 1993-1996
  • Bachelor Degree Graduation Honor: Faculty of Medicine, Cairo University, Cairo, Egypt. - 1999
  • Master’s Degree Honor of Excellence: Children’s Hospital, Cairo University, Cairo, Egypt. - 2004
  • Doctoral Degree Honor of Excellence: National Cancer Institute, Cairo University, Cairo, Egypt. - 2010
  • The Brooklyn Hospital Center’s service excellence standards and behaviors. - 2012
  • The Brooklyn Hospital Center’s best resident. - 2013
  • The Brooklyn Hospital Center’s best teacher. - 2013
  • Young Investigation Travel Award ASPHO/PBMTC. - 2015
  • Certificate of recognition from the peers: Fellowship graduation ceremony. MD Anderson Cancer Center. - 2016

Membership in professional Societies

  • American Society of Neuro Oncology (SNO): Member - 2017- Present
  • American Society of Hematology (ASH): Member - 2013- Present
  • American Society of pediatric Hematology and Oncology (ASPHO): Member - 2013- Present
  • American Society of Clinical Oncology (ASCO): Member - 2013- Present
  • Egyptian Medical Syndicate: Member. - 2000- Present

Acanda, A.M., Berlow, N.E., ..., Maher, O., et al (2024). Feasibility of functional precision medicine for guiding treatment of relapsed or refractory pediatric cancers. Nature medicine, 30(4), 990-1000. View in Pubmed

De Avila, C., Martinez, P., ..., Maher, O., et al (2024). Hematopoietic Stem Cell Transplantation in Children with Sickle Cell Disease and Thalassemia Major: A National Database Study. Pediatric Hematology Oncology, 41(7), 489-503. View in Pubmed

Wu, Z., Dazelle, K., ..., Maher, O., et al (2024). Papillary tumor of the pineal region: analysis of DNA methylation profiles and clinical outcomes in 76 cases. Acta neuropathologica communications, 12(1), 117. View in Pubmed

Silva, M.A., Mirchia, K., ..., Maher, O.M., et al (2022). Disseminated diffuse midline glioma associated with poorly differentiated orbital lesion and metastases in an 8-year-old girl: case report and literature review. Child's nervous system, 38(10), 2005-2010. View in Pubmed

Lucas, C.G., Sloan, E.A., ..., Maher, O.M., et al (2022). Multiplatform molecular analyses refine classification of gliomas arising in patients with neurofibromatosis type 1. Acta neuropathologica, 144(4), 747-765. View in Pubmed

Lu, V.M., Eichberg, D.G. ..., Maher, O.M., et al (2022). Distinct survival and clinical profile of infantile glioblastoma: insights from a national database. Child's nervous system, 38(1), 85-94. View in Pubmed

Lu, V.M., Di, L. ..., Maher, O.M., et al (2022). Contemporary outcomes of diffuse leptomeningeal glioneuronal tumor in pediatric patients: A case series and literature review. Clinical neurology and neurosurgery, 218(), 107265. View in Pubmed

Durno, C., Ercan, A.B. ..., Maher, O.M., et al (2021). Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance. Journal of clinical oncology, 39(25), 2779-2790. View in Pubmed

Lu, V.M., Di, L., ..., Maher, O.M., et al (2021). Age of diagnosis clinically differentiates atypical teratoid/rhabdoid tumors diagnosed below age of 3 years: a database study. Pediatric Neurosurgery, 37(4), 1077-1085. View in Pubmed

Shah, S., Gates, K., ..., Maher, O.M., et al (2021). Effect of Postoperative Radiation Therapy Timing on Survival in Pediatric and Young Adult Ependymoma. Advances in radiology oncology, 26(4), 100691. View in Pubmed

Mondal, G., Lee, J.C., ..., Maher, O.M., et al (2020). Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition. Acta neuropathologica, 139(6), 1071-1088. View in Pubmed

Elborai, Y., Almutereen, M., Maher, O.M., et al (2020). Changes in glomerular filtration rate and clinical course after sequential doses of carboplatin in children with embryonal brain tumors undergoing autologous stem cell transplantation. Journal of the Egyptian National Cancer Institute, 32(1), 9. View in Pubmed

Febres-Aldana, C., Pelaez, L. ..., Maher, O.M., et al (2020). A Case of UDP-Galactose 4'-Epimerase Deficiency Associated with Dyshematopoiesis and Atrioventricular Valve Malformations: An Exceptional Clinical Phenotype Explained by Altered N-Glycosylation with Relative Preservation of the Leloir Pathway. Molecular syndromology, 11(5-6), 320-329. View in Pubmed

Eterovic, A.K., Maher, O.M., Chandra J., et al (2018). Metachronous Medulloblastoma in a Child With Successfully Treated Neuroblastoma: Case Report and Novel Findings of DNA Sequencing. Journal of the National Comprehensive Cancer Network , 16(6), 683-691. View in Pubmed

Sridhar, D.C., Maher, O.M., Rodriguez, N.I. (2018). Pediatric Deep Venous Thrombosis Associated With Staphylococcal Infections: Single Institutional Experience. Journal of pediatric hematology/oncology, 40(2), e73-e76. View in Pubmed

Pekmezci,, M., Villanueva-Meyer, J.E., Goode, B., ..., Maher, O.M., et al (2018). The genetic landscape of ganglioglioma. Acta neuropathologica communications, 6(1), 47. View in Pubmed

Maher, O.M., Silva, J.G., Huh, W.W., et al (2017). Etiologies and Impact of Readmission Rates in the First 180 Days After Hematopoietic Stem Cell Transplantation in Children, Adolescents, and Young Adults. Journal of pediatric hematology/oncology, 39(8), 609-613. View in Pubmed

Galvez-Silva, J., Maher, O.M., Park, M. (2017). Prognostic Analysis of Absolute Lymphocyte and Monocyte Counts after Autologous Stem Cell Transplantation in Children, Adolescents, and Young Adults with Refractory or Relapsed Hodgkin Lymphoma. Biology of blood and marrow transplantation , 23(8), 1276-1281. View in Pubmed

Maher, O.M., Silva, J.G., Wu, J., et al (2017). Outcomes of children, adolescents, and young adults following allogeneic stem cell transplantation for secondary acute myeloid leukemia and myelodysplastic syndromes-The MD Anderson Cancer Center experience. Pediatric transplantation, 21(3), . View in Pubmed

Maher, O.M., Khatua, S., Mukherjee, D., et al (2016). Primary intracranial soft tissue sarcomas in children, adolescents, and young adults: single institution experience and review of the literature. Journal of Neuro-oncology, 127(1), 155-163. View in Pubmed

Maher O.M., Moonat, H.R. (2016). Fanconi Anemia and Fanconi Syndrome: Time to Correct the Misnomers. Journal of pediatric hematology/oncology, 38(7), 585. View in Pubmed

Maher, O.M., Alousi, A.M., Cooper, L.J.N., et al (2015). Regulatory T Cells and Their Implications in Graft-versus-Host Disease. Translational Science, 1(1), e01.

Maher, O.M., Christensen, A.M., Yedururi, S., et al (2015). Histone deacetylase inhibitor for NUT midline carcinoma. Pediatric blood cancer, 62(4), 715-717. View in Pubmed

Maher, O.M., Prieto, V.G., Stewart, J., Herzog, C.E. (2015). Characterization of metastatic angiomatoid fibrous histiocytoma. Journal of pediatric hematology/oncology, 37(4), e268-e271. View in Pubmed

Silva, J.G., Corrales-Medina, F.F., Maher, O.M., et al (2015). Clinical next generation sequencing of pediatric-type malignancies in adult patients identifies novel somatic aberrations. Oncoscience, 2(2), 187-192. View in Pubmed

Maher, O.M., Marco, S.A., Sadanandan, S., et al (2014). Retroperitoneal ganglioneuroma and reversible posterior leukoencephalopathy in a child with acute lymphoblastic leukemia. Journal of pediatric hematology/oncology, 36(8), 665-666. View in Pubmed

Moonat, H.R., Maher, O.M., Silva, J.G., et al (2014). Infection Mimicking Malignancy: Two Cases to Learn From. Progressive science,

Hussein, M.H.M., El-Haddad, A.M., Moussa, H.S., Maher, O.M. (2013). Prognostic Markers in Pediatric T-cell Lymphoblastic Leukemia/Lymphoma. Life Science Journal, 10(1), 1804-1813.

Oficina Principal

Dirección:
Kidz Medical Services, Inc.
3100 SW 62 Avenue -NE Wing #121
Miami, FL 33155
Número de Teléfono:
305-662-8360

Educación

Fellowship - Dana-Farber Cancer Institute
Fellowship - University of Texas
Residency - Brooklyn Hospital Center
Medical School - University of Cairo

Certificaciones

American Board of Pediatrics (Pediatrics) - Certified
American Board of Pediatrics (Ped Hemat-Onc) - Certified