HLA Typing by Next Generation Sequencing

Also known as: HLA sequencing.

What is HLA typing by next generation sequencing?

Human leukocyte antigens, or HLA, are proteins that the body produces in response to foreign invaders. As researchers understand more about HLA, they are able to answer many questions about the diagnosis and treatment of immune disorders. High-resolution HLA typing by next generation sequencing is a cutting edge, complex method of coding an individual’s entire HLA genetic makeup in order to better understand their unique immune response.


What happens during the procedure?

A routine blood draw is required in order to begin the HLA typing by next generation sequencing process. The blood sample is then taken to a laboratory, where the HLA genotyping by next generation sequencing process begins. It’s one of the most extensive genetic tests available.


Is any special preparation needed?

In most cases, no special preparation is needed for the test.


What are the risk factors?

Infection, bleeding and damage to surrounding organs and tissues are potential risks of any blood draw.


Reviewed by: Sajel L Kana, MD

This page was last updated on: March 26, 2019 12:26 PM