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Nicklaus Children’s Hospital has several outpatient and urgent care centers throughout South Florida, including on-demand, virtual care.
Walk-in urgent care with no appointment needed.
Serving as your child's primary doctor's office.
Pediatric specialty consultations available closer to home.
A full range of comprehensive services all under one roof.
Connect with providers from the comfort of your own home.
With over 800 pediatric clinicians on staff, we’re dedicated to helping you connect with the right specialist for your needs.
We have expertise in treating children and educating families on hundreds of different conditions.
We use cutting-edge, specialized treatments and procedures to ensure the best care for your child.
Also known as: AS.
Angelman syndrome is a rare genetic disorder that begins to show symptoms around 6 to 12 months of age. Children with Angelman syndrome have global developmental delays, seizures and excitable, happy personalities as a general rule.
Angelman syndrome is a genetic disorder. It's usually caused by problems with a gene located on chromosome 15 called the ubiquitin protein ligase E3A (UBE3A) gene
Angelman syndrome can also be caused by a chromosomal rearrangement called a translocation, or by a mutation or other defect in the region of DNA that controls activation of the UBE3A gene. These genetic changes can abnormally turn off (inactivate) UBE3A or other genes on the maternal copy of chromosome 15.
Angelman syndrome signs and symptoms include:
Developmental delays, including no crawling or babbling at 6 to 12 months
Intellectual disability
No speech or minimal speech
Difficulty walking, moving or balancing well (ataxia)
Seizures
Microcephaly
Happy, excitable personality
Reviewed by: Parul B Jayakar, MD
This page was last updated on: December 28, 2021 12:14 PM