Rhabdomyosarcoma

Also known as: RMS, childhood rhabdomyosarcoma.

What is rhabdomyosarcoma?

Rhabdomyosarcoma is a type of soft tissue cancer that can affect any of the skeletal muscles, or voluntary muscles (the muscles that one can control), of the body occurring in boys more often than girls (mostly younger than 15 years of age).

Several microscopic groups exist which have importance in how the sarcoma responds to treatment.

What causes rhabdomyosarcoma?

Certain chromosomal/genetic changes seem to lead to the development of rhabdomyosarcoma, but researchers aren’t exactly sure why these mutations occur.

What are the symptoms of rhabdomyosarcoma?

The symptoms of rhabdomyosarcoma vary widely depending on its size and where it occurs, in the body. As the tumor grows, it can put pressure on surrounding body parts and lead to swelling, pain, bulging eyes, sinus pressure and other symptoms.

What are rhabdomyosarcoma care options?

Treatments include surgery, chemotherapy and radiation.


Reviewed by: Jack Wolfsdorf, MD, FAAP

This page was last updated on: June 28, 2022 02:37 PM

Sarcoma and Solid Tumor Program

The program combines the expertise of the Orthopedic, Sports Health & Spine Institute and the Shaham Cancer & Blood Disorders Institute for the best outcomes.

Learn More

Setting the Gold Standard: Advancing Care for Sarcoma and Solid Tumors

November 29, 2023 – Bone and joint cancers account for a fraction of cancer cases in the U.S., and their rarity and a paucity of treatment options underscore the need for experienced, multidisciplinary care and novel solutions. Nicklaus Children's Hospital's Sarcoma and Solid Tumor Program delivers both options for children with these malignancies.